近日，國(guo)(guo)藥(yao)(yao)(yao)(yao)工業(ye)收到國(guo)(guo)家藥(yao)(yao)(yao)(yao)品(pin)監督管理(li)局(ju)簽發的《藥(yao)(yao)(yao)(yao)品(pin)補充申請(qing)批準通知書》，其硝苯地(di)平(ping)緩釋片（Ⅱ）20mg（藥(yao)(yao)(yao)(yao)品(pin)批準文(wen)號：國(guo)(guo)藥(yao)(yao)(yao)(yao)準字H20237166）通過仿制藥(yao)(yao)(yao)(yao)質(zhi)量和療(liao)效一(yi)致性評價。

硝苯地(di)平(ping)是一種二氫吡啶類鈣拮抗(kang)劑，主(zhu)要(yao)治療慢性穩定型(xing)(xing)心(xin)(xin)(xin)(xin)(xin)絞痛(tong)（勞累型(xing)(xing)心(xin)(xin)(xin)(xin)(xin)絞痛(tong)）、血(xue)管(guan)痙攣型(xing)(xing)心(xin)(xin)(xin)(xin)(xin)絞痛(tong)（Prinzmetal’s心(xin)(xin)(xin)(xin)(xin)絞痛(tong)、變異型(xing)(xing)心(xin)(xin)(xin)(xin)(xin)絞痛(tong)）和(he)原發性高血(xue)壓(ya)(ya)。硝苯地(di)平(ping)抑制與肌肉興奮收(shou)縮偶(ou)聯有關的物質Ca進入血(xue)管(guan)平(ping)滑肌細胞以及(ji)心(xin)(xin)(xin)(xin)(xin)肌細胞，擴張(zhang)冠狀動脈同(tong)時減(jian)(jian)少(shao)總外周(zhou)(zhou)血(xue)管(guan)阻力，發揮抗(kang)高血(xue)壓(ya)(ya)作用(yong)與改善心(xin)(xin)(xin)(xin)(xin)肌酶供需平(ping)衡作用(yong)。通過擴張(zhang)全身小動脈來減(jian)(jian)少(shao)總外周(zhou)(zhou)血(xue)管(guan)阻力，發揮穩定且持續的降壓(ya)(ya)作用(yong)。

此次過評，將進(jin)一(yi)步提升國藥工業硝苯地(di)平(ping)緩釋片（Ⅱ）的市場(chang)競爭力(li)。